Science

Probably maybe: Ice cream variation

ice cream cones

The saying goes that “probabilities are counter-intuitive”. A simple problem might appear to have a straightforward answer at first glance, but only do we later learn, through careful explanation, that our intuition has been subverted. Indeed, human intuition is rarely to be trusted when it comes to making probabilistic judgments, especially under time pressure. Even those trained in statistics, like most readers of Significance, can fall prey to cognitive biases when making snap decisions.

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Preventing cancer: mere rhetoric or a promising plan?

CT scan

In December 1971, two years after the successful Apollo 11 moon landing, US President Richard Nixon launched a “war on cancer” with the signing of the National Cancer Act. Since that time, billions of dollars and thousands of careers have been devoted to finding ways to prevent or cure the disease. But the fight is not yet over.

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What is the bootstrap?

Bradley Efron

Bradley Efron (pictured) was awarded the 2018 International Prize in Statistics for the creation of the “bootstrap”, a method that “transformed science’s ability to use and understand data and helped usher in the era of data analysis through computing”. But what is the bootstrap? James J. Cochran explains.

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Misunderstanding the global burden of alcohol

Beer in fridge

Harmful alcohol consumption is known to cause several diseases and many deaths. A study published in the Lancet this August has presented the latest figures, pertaining to the year 2016.1 The authors estimate that alcohol answers for approximately 7% of all male and 2% of all female deaths, as well as 6% of male and 2% of female disability-adjusted life year losses. Moreover, respective estimates were presented for all countries over several years. But these estimates seem to be too high.

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Toby Lewis at 100

Toby Lewis

On 19 October 2018, in a West London care home, Toby Lewis turned 100. Physically fit, if a bit frail, he looks and sounds as anyone who had not seen him for 40 years would recognise instantly. He greets you with the same polite, gentlemanly air that always masked a certain eccentricity, even anarchism, that made him such an interesting and lively companion.

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